Emmanuel O. Olawode
Education and Training
- B. Pharm., Obafemi Awolowo University Ile-Ife, Nigeria
- MSc. Pharmacognosy, Obafemi Awolowo University Ile-Ife, Nigeria
- Ph.D. Pharmaceutical Chemistry, Rhodes University Grahamstown, South Africa
- Postdoctoral Fellowship, Department of Chemistry, Rhodes University, Grahamstown, South Africa
- Postdoctoral Fellowship, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa
- Presidential Diversity College of Pharmacy, Johnson City/Binghamton
- Postdoctoral Fellowship Binghamton University NY, USA
Teaching Interests
Dr. Olawode’s teaching interests and experience include medicinal and pharmaceutical chemistry and pharmacognosy. Other teaching experiences include introductory biochemistry and immunology, herbal medicine, and non-sterile pharmaceutical compounding.
Scholarly Interests
Dr. Olawode’s broad research areas include drug discovery and development, metabolomics and natural products. His work in drug discovery and development involves organic synthesis of small molecules, small peptides, and antibody drug conjugates (ADCs) for cancer, neurodegenerative disorders and certain infectious diseases such as tuberculosis. Dr. Olawode’s interests in neurodegenerative drug discovery is focused on small linear and cyclic heterocyclic peptides with potential neuro-proliferation and differentiation properties. Dr. Olawode’s interests in metabolomics include drug metabolomics of clinical samples aimed at developing biomarkers as tools for monitoring pharmacokinetic and pharmacodynamic (PK-PD) in therapeutic drug monitoring and precision medicine. His previous work in foodomics and plantomics highlighted chemical markers for standardization of natural health products. His focus on antibody drug conjugates (ADCs) involves preparation of potent payloads and novel analogues, development of new linkers, preparation of corresponding ADCs and their characterization using high throughput analytical methods such as LC-MS and NMR.
Selected Recent Publications
- Umumararungu T, Mukazayire MJ, Mpenda M, Mukanyangezi MF, Nkuranga JB, Mukiza J, Olawode EO. A review of recent advances in anti-tubercular drug development. Indian Journal of Tuberculosis 67(4):539-559 (2020).
- Olawode EO, Tandlich T, Prinsloo E, Isaacs M, Hoppe H, Ronnett Seldon, Warner DF, Steenkamp F, Kaye PT. Synthesis and biological evaluation of 2-chloro-3-[(thiazol-2-yl)amino]-1,4-naphthoquinones. Bioorganic & Medicinal Chemistry Letters 29(13):1572 (2019).
- Olawode EO, Tandlich R, Cambray G. ¹H-NMR Profiling and Chemometric Analysis of Selected Honeys from South Africa, Zambia, and Slovakia. Molecules 5;23(3):578 (2018).
- Olayiwola G, Ukponmwan O, Olawode D. Sedative and anxiolytic effects of the extracts of the leaves of Stachytarpheta cayennensis in mice. African Journal of Traditional Complementary Alternative Medicine 10(6):568-79 (2013).
- Adebajo AC, Olawode EO, Omobuwajo OR, Adesanya SA, Begrow F, Elkhawad A, Akanmu MA, Edrada R, Proksch P, Schmidt TJ, Klaes M, Verspohl EJ. Hypoglycaemic constituents of Stachytarpheta cayennensis leaf. Planta Medica 73(3):241-50 (2007).
Publication list via PubMed:
https://pubmed.ncbi.nlm.nih.gov/?term=Olawode
Awards and Honors
- Presidential Diversity Postdoctoral Fellowship (SUNY University at Binghamton, NY, USA)
- Postdoctoral Fellowship (Rhodes University, South Africa)
- Postdoctoral Fellowship (Medical Research Council flagship postdoctoral fellowship, Rhodes University, South Africa)
- Henderson PhD award (Rhodes University, South Africa)
- Federal postgraduate award, Masters category (Federal Government of Nigeria)
