Dedeepya Pasupuleti
Education and Training
B.Pharm. Sri Padmavathi Mahila Viswa Vidyalayam Tirupathi, India
M.S. New Mexico State University Las Cruces, New Mexico
Ph.D. Mercer University Atlanta, Georgia
Pharmaceutical Sciences College of Pharmacy
Teaching Interests
Dr. Pasupuleit’s teaching interests include various topics in Pharmaceutics and Pharmacology, such as formulation and drug delivery systems, biopharmaceutics, pharmacokinetics etc.
Scholarly Interests
Dr. Dedeepya Pasupuleti’s research focuses on nanotechnology, immunopharmaceutical science, breast cancer studies and analytical chemistry. Her research includes development of polymeric microparticulate and nanosphere-based vaccine delivery and targeted drug delivery systems. These are tailored for non-invasive administration routes, including microneedles, buccal films, and 3D-printed oral dissolving films. Her studies involve evaluation of vaccine efficiency via in vitro assays for antigen presentation and T-cell activation, as well as in vivo evaluation of humoral and cellular immune responses in mice. She also explores brain-targeted drug delivery using nanoparticle-encapsulated therapeutics for small molecule drugs. She also works on trace analysis with instrumentation such as liquid chromatography–tandem mass spectrometry (LC-MS/MS), differential mobility spectrometry (DMS), and gas chromatography, development of advanced ion filtering techniques and stabilization of compensation voltages to improve resolution and reproducibility in ambient pressure ion mobility systems. In addition, as a member of Rho Chi, she actively contributes to mentorship and teaching while exploring innovative pedagogical strategies in pharmacy education. Her work reflects a broad commitment to precision medicine, advanced analytical instrumentation, and translational science education.
Selected Publications
· Pasupuleti D, Bagwe P, Ferguson A, Uddin MN, D’Souza MJ, Zughaier SM. Evaluating Nanoparticulate Vaccine Formulations for Effective Antigen Presentation and T-Cell Proliferation Using an In Vitro Overlay Assay. Vaccines. 2024; 12(9):1049. https://doi.org/10.3390/vaccines12091049
· Pasupuleti D, Tro N, and Rita N. “Online Cancer Genomics Databases Provide Teaching Resources For Pharmacy Education.” American Journal of Pharmaceutical Education, September 10, 2021, 8683.https://doi.org/10.5688/ajpe8683.
· Adediran, E.; Arte, T.; Pasupuleti, D.; Vijayanand, S.; Singh, R.; Patel, P.; Gulani, M.; Ferguson, A.; Uddin, M.; Zughaier, S.M.; et al. Delivery of PLGA-Loaded Influenza Vaccine Microparticles Using Dissolving Microneedles Induces a Robust Immune Response. Pharmaceutics 2025, 17, 510. https://doi.org/10.3390/pharmaceutics17040510
· Eiceman, G.A., G. Lee, M. Menlyadiev, P.E. Fowler, D. Pasupuleti, S. Holopainen, U. Chiluwal, and H. Shokri. “Tandem Mobility Spectrometry at Ambient Pressure.” In Comprehensive Analytical Chemistry, 83:23–50. Elsevier, 2019. https://doi.org/10.1016/bs.coac.2018.11.002.
· Pasupuleti D, Gary A. Eiceman, and Karisa M. Pierce. “Classification of Biodiesel and Fuel Blends Using Gas Chromatography – Differential Mobility Spectrometry with Cluster Analysis and Isolation of C18:3 Me by Dual Ion Filtering.”Talanta 155 (August 2016): 278–88. https://doi.org/10.1016/j.talanta.2016.04.044.
· Pasupuleti, D., K. Pierce, and G.A. Eiceman. “Gas Chromatography with Tandem Differential Mobility Spectrometry of Fatty Acid Alkyl Esters and the Selective Detection of Methyl Linolenate in Biodiesels by Dual-Stage Ion Filtering.” Journal of Chromatography A 1421 (November 2015): 162–70. https://doi.org/10.1016/j.chroma.2015.09.017
Publication list via PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Dedeepya+Pasupuleti
Selected Recent Presentations
· Pasupuleti, D.; “A Rapid High Through-Put Immune Mimicking Platform for Vaccine Evaluation” Rapid Fire Presentation; Pharm Sci 360 (AAPS) 2024; October 2024, Salt Lake City, UT, USA.
· Pasupuleti, D.; Ferguson, A.; Bagwe, P.; Zughaier, S.; D’Souza, M.J.; “A cell-to-cell contact immune system mimicking in vitro overlay assay: Evaluating nanoparticle vaccine formulations for adaptive immunity responses” Pharm Sci 360 (AAPS) 2024; October 2024, Salt Lake City, UT, USA.
· Pasupuleti. D.; D’Souza. M.; Ferguson. A.; Adediran. E.; & D’Souza, M. J.; Pioneering the Targeted Brain Delivery of Aspirin to Elicit COX-1&2 Inhibition, Protecting from Ischemic Stroke And Neurodegeneration, Pharm Sci 360 (AAPS) 2024; October 2024, Salt Lake City, UT, USA.
· Pasupuleti, D.; Zughaier, S.; D’Souza, M.J.; “Development of a rapid high throughput immune mimicking assay for nanoparticulate vaccine evaluation” American Chemical Society, SERMACS, 2024; October 2024, Atlanta, GA, USA.
· Pasupuleti, D.; D’Souza Marissa; D’Souza, M.J.; “Enhancing targeted drug delivery to the brain: Development of Microfluidics-assisted sustained release nanoparticulate system for
Aspirin and characterization using LC-MS/MS” American Chemical Society, SERMACS, 2024; October 2024, Atlanta, GA, USA
Awards and Honors
· Winner, 1st place, Monroe F. Swilley, Jr. Student Research Award, Mercer University, March 2024.
· Winner COP-SOM Joint Research Conference, Mercer University, October 2023.
· Winner of Anthony Shumer Scientific Poster Awards – Georgia Bio Summit, November 1st, 2023.
· Rho-Chi Honor Society – 2025
